Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968101 | 0.78 | KDM4E (0.61) | DCTPP1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL22469017 | 0.77 | GUSB (0.46) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL971700 | 0.77 | ALDH1A1 (0.49) | LMNADCTPP1ALDH1A1MAPK1KDM4E | |
| SCHEMBL11025136 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL970693 | 0.77 | ALDH1A1 (0.62) | HDAC1HDAC2LMNAALDH1A1MAPK1 | |
| SCHEMBL28587679 | 0.77 | ALDH1A1 (0.65) | HDAC1HDAC2ALDH1A1KDM4EHPGD | |
| SCHEMBL1531740 | 0.74 | PTPN11 (0.47) | HDAC1HDAC2LMNADCTPP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11567022 | 0.73 | HDAC1 (0.50) | HDAC1HDAC2LMNADCTPP1ALDH1A1 | |
| SCHEMBL969067 | 0.73 | ESR2 (0.40) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL971940 | 0.73 | KDM4E (0.66) | ALDH1A1KDM4EHPGDHSD17B10AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483412-B | Synthetic method of rosuvastatin tert-butyl ester | 安徽省庆云医药股份有限公司 | 2020-06-26 | — | — | CN | disclosed |
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |