Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432637 | 0.80 | TTR (0.71) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL11220754 | 0.79 | TTR (0.60) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL3453760 | 0.79 | MAPT (0.66) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL4054817 | 0.79 | MAPT (0.59) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL11335735 | 0.78 | TTR (0.53) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL7096608 | 0.76 | PKLR (0.71) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL27642810 | 0.76 | MAPT (0.64) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL68338 | 0.75 | TTR (0.64) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL7055073 | 0.75 | TTR (0.55) | TTRALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL11278222 | 0.74 | CYP3A4 (0.40) | TTRALDH1A1L3MBTL1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499450-A1 | Synthesis of 1-aminoanthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| EP-0499451-A1 | Synthesis of 1-amino-anthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5132437-A | From 2-Substituted Benzyl Compound and Xylene | HOECHST CELANESE CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-5130448-A | Condensing ortho substituted benzoic acid and xylene, oxidation, ring closure, ammonolysis and decarboxyalation | HOECHST CELANESE CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |