Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630736 | 0.98 | ALDH1A1 (0.55) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL10824560 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| (Chloromethyl)Benzene SCHEMBL7196363 | 0.90 | HNF4A (0.47) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL29383769 | 0.87 | TSHR (0.46) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL11044630 | 0.87 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL27488099 | 0.87 | ALDH1A1 (0.54) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL27543078 | 0.84 | LIG1 (0.49) | ALDH1A1HNF4ATSHRTDP1KMT2A | |
| SCHEMBL9244765 | 0.84 | HNF4A (0.59) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL11213066 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL9076064 | 0.82 | LTB4R (0.52) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0329460-B1 | STABILISED MACROLIDE COMPOSITIONS | AMERICAN CYANAMID COMPANY (US) | 1992-05-20 | — | — | EP | claimed |