Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | THRB | P10828 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 5/20 | 0.49 |
| ▸ | GRK6 | P43250 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462340 | 0.80 | KMT2A (0.61) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL18984665 | 0.79 | MAOA (0.63) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL6157627 | 0.79 | MAPT (0.62) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL11120139 | 0.78 | MCL1 (0.61) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL10947122 | 0.78 | KMT2A (0.45) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL27691621 | 0.78 | MAPT (0.60) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL11220754 | 0.77 | TTR (0.60) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL18984773 | 0.76 | MCL1 (0.61) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL3955176 | 0.75 | BCL2 (0.67) | MAPTKMT2AMEN1MCL1MAPK1 | |
| SCHEMBL11356483 | 0.75 | MAOA (0.53) | MAPTKMT2AMEN1MCL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499450-A1 | Synthesis of 1-aminoanthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| EP-0499451-A1 | Synthesis of 1-amino-anthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5132437-A | From 2-Substituted Benzyl Compound and Xylene | HOECHST CELANESE CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| US-5130448-A | Condensing ortho substituted benzoic acid and xylene, oxidation, ring closure, ammonolysis and decarboxyalation | HOECHST CELANESE CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |