Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ESRRA | P11474 | 2/20 | 0.53 |
| ▸ | RARB | P10826 | 2/20 | 0.53 |
| ▸ | RARG | P13631 | 2/20 | 0.53 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154079 | 0.84 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1ALDH1A1LMNAESRRA | |
| SCHEMBL384263 | 0.82 | RARB (0.71) | HSP90AA1HSP90AB1ALDH1A1ALOX15NR1I2 | |
| SCHEMBL1730526 | 0.82 | ESRRA (0.68) | HSP90AA1HSP90AB1ALDH1A1ALOX15NR1I2 | |
| SCHEMBL29654169 | 0.82 | RARB (0.71) | HSP90AA1HSP90AB1ALDH1A1ALOX15NR1I2 | |
| SCHEMBL28059045 | 0.81 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1LMNACYP2C9HTT | |
| SCHEMBL13044197 | 0.81 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1ALDH1A1ALOX15NR1I2 | |
| SCHEMBL15505390 | 0.81 | TSHR (0.39) | HSP90AA1HSP90AB1ALDH1A1LMNAESRRA | |
| SCHEMBL5373229 | 0.81 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1ALDH1A1ALOX15NR1I2 | |
| SCHEMBL4895466 | 0.81 | P4HB (0.47) | HSP90AA1HSP90AB1HSD17B10CYP1A2 | |
| SCHEMBL10428423 | 0.79 | SIRT1 (0.54) | HSP90AA1HSP90AB1ALDH1A1ALOX15NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162405-A | Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5013777-A | Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers | ATOCHEM NORTH AMERICA, INC. (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0332761-A2 | Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1989-09-20 | — | — | EP | disclosed |