Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201000 | 0.87 | MEN1 (0.60) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL10340685 | 0.87 | MEN1 (0.60) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL9403709 | 0.86 | MEN1 (0.55) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL11700396 | 0.85 | LMNA (0.61) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL16074981 | 0.85 | MEN1 (0.58) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL29096779 | 0.85 | ALOX15 (0.40) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL12999684 | 0.83 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL7034495 | 0.83 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL14047326 | 0.83 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA | |
| SCHEMBL13057738 | 0.83 | MEN1 (0.56) | MEN1CYP3A4ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153344-A | Vitamin E intermediates and a process for their manufacture and conversion into vitamin E | HOFFMAN-LA ROCHE INC. (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0269009-B1 | METHOD FOR THE PRODUCTION OF CARBINOL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-31 | — | — | EP | disclosed |
| US-5034546-A | Novel vitamin E intermediates and a process for their manufacture and conversion into vitamin E | HOFFMANN-LA ROCHE INC. (US) | 1991-07-23 | — | — | US | disclosed |
| EP-0269009-A2 | Method for the production of carbinol derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-06-01 | — | — | EP | disclosed |