Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22852093 | 0.80 | RAPGEF4 (0.39) | RAPGEF4MAPTTDP1ALDH1A1KDM4E | |
| SCHEMBL346242 | 0.80 | ALDH1A1 (0.48) | RAPGEF4CA12CA1CA2MAPT | |
| SCHEMBL9080020 | 0.79 | ENPP2 (0.59) | RAPGEF4CA12CA1CA2CA4 | |
| SCHEMBL29899149 | 0.79 | ENPP2 (0.59) | RAPGEF4CA12CA1CA2CA4 | |
| SCHEMBL9080026 | 0.79 | ENPP2 (0.59) | RAPGEF4CA12CA1CA2CA4 | |
| SCHEMBL9079841 | 0.79 | EGFR (0.41) | RAPGEF4CA12CA1CA2CA4 | |
| SCHEMBL21589354 | 0.78 | TNNI3 (0.46) | RAPGEF4CA12CA1CA2CA4 | |
| SCHEMBL11690188 | 0.78 | CYP3A4 (0.41) | CA1CA2CA9MAPTTDP1 | |
| SCHEMBL10064489 | 0.77 | RAPGEF4 (0.40) | RAPGEF4CA12CA1CA2CA4 | |
| SCHEMBL19750554 | 0.75 | RAPGEF4 (0.54) | RAPGEF4CA12CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091466-A | Insolubilization of soluble pre-imidized polyimides by polyhydrazine compounds | GENERAL ELECTRIC COMPANY (US) | 1992-02-25 | — | — | US | disclosed |