SCHEMBL9717408

SCHEMBL9717408

C=C(c1ccccc1)C(C)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.47
LMNA P02545 4/20 0.47
NPSR1 Q6W5P4 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 3/20 0.45
XBP1 P17861 1/20 0.45
ATM Q13315 1/20 0.45
PTGS2 P35354 3/20 0.43
PTGS1 P23219 2/20 0.43
CXCR1 P25024 2/20 0.43
CXCR2 P25025 2/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 2/20 0.43
THPO P40225 2/20 0.43
KDM4E B2RXH2 2/20 0.43
HIF1A Q16665 2/20 0.43
RECQL P46063 1/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
PMP22 Q01453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2025812 0.85 TSHR (0.50) SMN1; SMN2LMNANPSR1ALDH1A1MAPT
SCHEMBL28543627 0.83 NPC1 (0.56) SMN1; SMN2NPSR1ALDH1A1MAPTPTGS2
SCHEMBL21854831 0.83 LMNA (0.49) SMN1; SMN2LMNANPSR1ALDH1A1MAPT
SCHEMBL30300820 0.83 LMNA (0.49) SMN1; SMN2LMNANPSR1ALDH1A1MAPT
SCHEMBL4909396 0.78 LMNA (0.45) SMN1; SMN2LMNANPSR1ALDH1A1MAPT
SCHEMBL13177031 0.78 PTGS2 (0.45) LMNAALDH1A1PTGS2PTGS1CYP3A4
SCHEMBL16168604 0.78 PTGS2 (0.45) LMNAALDH1A1PTGS2PTGS1CYP3A4
SCHEMBL13176481 0.78 PTGS2 (0.45) LMNAALDH1A1PTGS2PTGS1CYP3A4
SCHEMBL693987 0.78 SMN1; SMN2 (0.50) SMN1; SMN2LMNANPSR1ALDH1A1MAPT
SCHEMBL11798431 0.77 MAPT (0.45) SMN1; SMN2LMNANPSR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0311689-A1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-04-19 EP claimed
EP-0304495-A1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-01 EP claimed
CN-109016572-B Method and system for reducing volatile compound emissions in products 通用汽车环球科技运作有限责任公司 2020-12-18 CN disclosed
US-10358540-B2 Process and system for reducing volatile compound emissions from a product GM Global Technology Operations LLC (US) 2019-07-23 US disclosed
CN-109016572-A Reduce the method and system of volatile compound discharge in product 通用汽车环球科技运作有限责任公司 2018-12-18 CN disclosed
US-20180355141-A1 PROCESS AND SYSTEM FOR REDUCING VOLATILE COMPOUND EMISSIONS FROM A PRODUCT GM Global Technology Operations LLC 2018-12-13 US disclosed
EP-0311689-B1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1992-06-10 EP disclosed
US-4982007-A CARBONYLATION CATALYST NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-01-01 US disclosed
EP-0311689-A1 PROCESS FOR SELECTIVELY MONOHYDROFORMYLATING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-04-19 EP disclosed
EP-0304495-A1 PROCESS FOR SELECTIVELY MONOHYDROESTERIFYING DIOLEFIN NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-03-01 EP disclosed
EP-0174378-A1 Electrical-insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-03-19 EP disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed