Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.39 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21185839 | 0.92 | HPGD (0.50) | HPGDTDP1ACRKMT2AMEN1 | |
| SCHEMBL9717459 | 0.83 | MLYCD (0.49) | PARP1HPGDTDP1ACRKMT2A | |
| SCHEMBL1249570 | 0.83 | PARP1 (0.42) | PARP1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL30560902 | 0.83 | PARP1 (0.42) | PARP1HPGDTDP1KMT2AMEN1 | |
| SCHEMBL2854780 | 0.80 | HPGD (0.67) | PARP1HPGDTDP1TSHR | |
| SCHEMBL5935460 | 0.80 | HPGD (0.53) | HPGDACRKMT2AMEN1L3MBTL1 | |
| SCHEMBL2206850 | 0.78 | TP53 (0.51) | PARP1HPGDTDP1KMT2AMLYCD | |
| SCHEMBL10326041 | 0.77 | PARP1 (0.37) | PARP1HPGDTDP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3355966 | 0.76 | TP53 (0.50) | PARP1HPGDTDP1KMT2AMLYCD | |
| Hydrochloric Acid SCHEMBL3352609 | 0.76 | TP53 (0.50) | PARP1HPGDTDP1KMT2AMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086104-A | Mixture of thermoplastic resin, elastomer and amide compound, excellent toughtness, heat resistance and durability | POLYPLASTICS CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |