SCHEMBL30560902

SCHEMBL30560902

NC(=O)c1cccc(C(=O)N(CC(O)CO)CC(O)CO)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 9/20 0.42
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.40
HPGD P15428 1/20 0.40
CRY1 Q16526 1/20 0.39
CRY2 Q49AN0 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MEP1B Q16820 1/20 0.37
TNKS O95271 1/20 0.36
PARP15 Q460N3 1/20 0.36
PARP14 Q460N5 1/20 0.36
PARP10 Q53GL7 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
PARP2 Q9UGN5 1/20 0.36
BACE1 P56817 1/20 0.36
MAPT P10636 2/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1249570 1.00 PARP1 (0.42) PARP1TSHRTDP1HPGDCRY1
SCHEMBL9717441 0.83 PARP1 (0.46) PARP1TSHRTDP1HPGDCRY1
SCHEMBL6863468 0.82 TSHR (0.31) TSHRCYP3A4
Hydrochloric Acid SCHEMBL31143760 0.81 TSHR (0.30) TSHRCYP3A4
SCHEMBL4581154 0.78 PARP1 (0.47) PARP1TSHRTDP1HPGDMEN1
SCHEMBL16626251 0.77 SMN1; SMN2 (0.55) TSHRMEN1KMT2ACYP3A4TP53
SCHEMBL28382529 0.76 PARP1 (0.46) PARP1TSHRTDP1MEN1KMT2A
SCHEMBL2854780 0.76 HPGD (0.67) PARP1TSHRTDP1HPGDMAPT
SCHEMBL7656151 0.74 CASP3 (0.34) MEN1KMT2APOLBCYP2C19
SCHEMBL8896112 0.74 PARP1 (0.46) PARP1TSHRTDP1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768747-A Intermediate of ioversol and method for preparing ioversol 江苏宇田医药有限公司 2023-09-19 CN disclosed