Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1931997 | 0.80 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28112100 | 0.79 | TSHR (0.41) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL198128 | 0.77 | TSHR (0.59) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL28321896 | 0.77 | TSHR (0.39) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL8395128 | 0.77 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL5953828 | 0.76 | TSHR (0.68) | TSHRALDH1A1CYP3A4CA1CA2 | |
| SCHEMBL11529649 | 0.76 | ALDH1A1 (0.43) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3189199 | 0.76 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL611233 | 0.75 | — | — | |
| SCHEMBL1603614 | 0.75 | TSHR (0.55) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171784-A | Blends of vinyl chloride copolymers, phenoyx resins, hydroxy acrylate or methacrylate lactone adducts and acrylate-diisocyanate adducts; magnetic recording media | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0217410-B1 | PHOSPHORYLATED REACTION PRODUCTS AND COMPOSITIONS INCORPORATING SUCH PRODUCTS | UNION CARBIDE CORPORATION (US) | 1991-09-18 | — | — | EP | disclosed |
| EP-0375659-A2 | Phosphorylated reaction products and compositions incorporating such products | UNION CARBIDE CORPORATION (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0375660-A2 | Phosphorylated reaction products and compositions incorporating such products | UNION CARBIDE CORPORATION (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0217410-A2 | Phosphorylated reaction products and compositions incorporating such products | UNION CARBIDE CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |