SCHEMBL9717697

SCHEMBL9717697

Cc1cc([S])n2ncnc2n1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
ENPP1 P22413 1/20 0.59
KDM4E B2RXH2 5/20 0.54
MAPK1 P28482 3/20 0.54
LMNA P02545 2/20 0.54
MAPT P10636 2/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 1/20 0.54
TSHR P16473 1/20 0.54
HSD17B10 Q99714 1/20 0.54
CYP1A2 P05177 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GAA P10253 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ATM Q13315 1/20 0.49
POLB P06746 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259453 0.80 ALDH1A1 (1.00) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL864946 0.77 ALDH1A1 (0.67) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL272835 0.77 ALDH1A1 (0.67) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL609785 0.77 ALDH1A1 (0.67) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL5151528 0.77 ALDH1A1 (0.67) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL5164814 0.76 ALDH1A1 (0.65) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL8421909 0.76 ALDH1A1 (0.65) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL12395114 0.74 ALDH1A1 (0.62) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL9332373 0.74 ALDH1A1 (0.69) ALDH1A1ENPP1KDM4EMAPK1LMNA
SCHEMBL13064173 0.74 ALDH1A1 (0.62) ALDH1A1ENPP1KDM4EMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142029-A Redox system FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
US-4966900-A FOR MICROBISM THERAPY, BACTERIAL INFECTIONS SANKEI PHARMACEUTICAL COMPANY LTD. (JP) 1990-10-30 US disclosed
EP-0167168-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-11-15 EP disclosed
EP-0198438-B1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-18 EP disclosed
US-4770990-A Silver halide photographic light-sensitive material containing a compound capable of imagewise releasing a photographically useful group during development FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
US-4740453-A Silver halide photosensitive material containing a compound capable of releasing a photographically useful group FUJI PHOTO FILM CO., LTD. (JP) 1988-04-26 US disclosed
EP-0254495-A2 Beta-Lactam compound, method for preparing the same, medicinal composition for bacterially infectious disease therapy containing the same and intermediates for synthesis of the same SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) 1988-01-27 EP disclosed
EP-0198438-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1986-10-22 EP disclosed
EP-0167168-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1986-01-08 EP disclosed