Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496585 | 0.79 | MC4R (0.43) | ALDH1A1CTSSCTSKSMN1; SMN2LMNA | |
| SCHEMBL6266626 | 0.77 | ANPEP (0.44) | ALDH1A1KDM4ESGMS2CTSSCTSK | |
| SCHEMBL19658729 | 0.77 | CA1 (0.54) | ALDH1A1GFERSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL27882263 | 0.76 | POLB (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNAMTNR1A | |
| SCHEMBL4898182 | 0.76 | CTSS (0.61) | ALDH1A1KDM4ESGMS2CTSSCTSK | |
| SCHEMBL4898169 | 0.76 | CTSS (0.61) | ALDH1A1KDM4ESGMS2CTSSCTSK | |
| SCHEMBL4898191 | 0.76 | CTSS (0.61) | ALDH1A1KDM4ESGMS2CTSSCTSK | |
| SCHEMBL14065364 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4ECTSSCTSKMTNR1A | |
| SCHEMBL31724327 | 0.74 | KMT2A (0.44) | ALDH1A1KDM4ESMN1; SMN2LMNAPOLB | |
| SCHEMBL14761368 | 0.73 | SGMS2 (0.51) | ALDH1A1KDM4ESGMS2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079346-A | High uptake in heart, lipid soluble; myocardial perfusion imaging | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1992-01-07 | — | — | US | disclosed |
| WO-1991017168-A1 | GALLIUM-LABELLED IMAGING AGENTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1991-11-14 | — | — | WO | disclosed |