Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.60 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL876100 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL674717 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL7259108 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL22207094 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL22207466 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL22207358 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL22207439 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL22207445 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 | |
| SCHEMBL876206 | 1.00 | TSHR (0.65) | TSHRNR5A1CHRNB2CHRNA4SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | SYMRISE AG (DE) | 2024-08-06 | — | — | US | claimed |
| EP-3373895-B1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2020-08-19 | — | — | EP | claimed |
| CN-104414869-B | A kind of skin and/or hair whitening mixture | 西姆莱斯股份公司 | 2019-09-03 | — | — | CN | claimed |
| EP-3373895-A1 | REDUCTION OF STINGING SENSATION ON SKIN | Symrise AG (DE) | 2018-09-19 | — | — | EP | claimed |
| EP-2842607-B1 | A skin and/or hair whitening mixture | SYMRISE AG (DE) | 2018-05-30 | — | — | EP | claimed |
| WO-2017080625-A1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2017-05-18 | — | — | WO | claimed |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG (DE) | 2015-03-05 | — | — | US | claimed |
| EP-2842607-A1 | A skin and/or hair whitening mixture | Symrise AG (DE) | 2015-03-04 | — | — | EP | claimed |
| US-12378205-B2 | Process for the preparation of triazine intermediates and a process for the preparation of UV absorbers thereof | BASF SE (DE) | 2025-08-05 | — | — | US | disclosed |
| US-12291509-B2 | Process for the preparation of UV absorbers | BASF SE (DE) | 2025-05-06 | — | — | US | disclosed |
| US-12053537-B2 | Reduction of stinging sensation on skin | SYMRISE AG (DE) | 2024-08-06 | — | — | US | disclosed |
| EP-4401843-A1 | SOLID CLEANSING COMPOSITIONS AND METHODS FOR THE SAME | Colgate-Palmolive Company (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-112320766-B | Preparation method and application of hollow mesoporous inorganic oxide nanosphere solid alkali | 西南大学 | 2023-10-27 | — | — | CN | disclosed |
| WO-2023043703-A1 | SOLID CLEANSING COMPOSITIONS AND METHODS FOR THE SAME | COLGATE-PALMOLIVE COMPANY (US) | 2023-03-23 | — | — | WO | disclosed |
| WO-2017080625-A1 | REDUCTION OF STINGING SENSATION ON SKIN | SYMRISE AG (DE) | 2017-05-18 | — | — | WO | disclosed |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | SYMRISE AG (DE) | 2015-03-05 | — | — | US | disclosed |
| EP-2842607-A1 | A skin and/or hair whitening mixture | Symrise AG (DE) | 2015-03-04 | — | — | EP | disclosed |
| US-5142029-A | Redox system | FUJI PHOTO FILM CO., LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0167168-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0167168-A2 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12053537-B2 | Reduction of stinging sensation on skin | STING1, TYR, CUTA | TSHR 3687/4885NR5A1 1165/4885CHRNB2 317/4885 |
| US-20150064122-A1 | SKIN AND/OR HAIR WHITENING MIXTURE | TYR, AHR, CYP1B1 | TSHR 2845/4885NR5A1 139/4885CHRNB2 850/4885 |
| US-12378205-B2 | Process for the preparation of triazine intermediates and a process for the preparation of UV absorbers thereof | DHPS, UNG, UMPS | TSHR 1518/4885NR5A1 2592/4885CHRNB2 4784/4885 |
| US-12291509-B2 | Process for the preparation of UV absorbers | UNG, UROD, ERCC4 | TSHR 3523/4885NR5A1 2673/4885CHRNB2 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.