Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9717964 | 0.82 | TSHR (0.42) | PTAFRALDH1A1POLBMAPTGFER | |
| SCHEMBL9717962 | 0.82 | PTAFR (0.47) | PTAFR | |
| SCHEMBL9646940 | 0.81 | PTAFR (0.50) | PTAFR | |
| SCHEMBL9717853 | 0.79 | TBXAS1 (0.45) | ALDH1A1POLBMAPTGFER | |
| SCHEMBL9647843 | 0.76 | PTAFR (0.52) | PTAFR | |
| SCHEMBL9646361 | 0.73 | ALDH1A1 (0.43) | PTAFRALDH1A1POLBMAPTGFER | |
| SCHEMBL9646821 | 0.73 | TBXAS1 (0.56) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9646861 | 0.72 | TBXAS1 (0.55) | ALDH1A1 | |
| SCHEMBL9717959 | 0.72 | GPR119 (0.42) | ALDH1A1MAPT | |
| SCHEMBL8871099 | 0.72 | PTAFR (0.40) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5149704-A | Pyridyl- or thiazolidineaminesor ureas | ABBOTT LABORATORIES (US) | 1992-09-22 | — | — | US | disclosed |