Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 8/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.43 |
| ▸ | PTGFR | P43088 | 3/20 | 0.43 |
| ▸ | PTGIR | P43119 | 2/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | TFPI2 | P48307 | 5/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201397 | 0.76 | TBXA2R (0.55) | TBXA2R | |
| SCHEMBL10437533 | 0.76 | TBXA2R (0.55) | TBXA2R | |
| SCHEMBL9718969 | 0.74 | PTGER3 (0.36) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL1774349 | 0.73 | PTGER3 (0.52) | PTGER3PTGER2PTGER4PTGDRTBXA2R | |
| SCHEMBL9197070 | 0.73 | TBXA2R (0.57) | TBXA2RTFPI2TBXAS1LMNAKDM4E | |
| SCHEMBL249465 | 0.73 | LMNA (0.40) | TFPI2LMNAKDM4ETP53ALDH1A1 | |
| SCHEMBL8870983 | 0.71 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL8988219 | 0.71 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL8870972 | 0.71 | TBXA2R (0.47) | TBXA2R | |
| SCHEMBL6685158 | 0.71 | HPGD (0.47) | PTGER3PTGER2PTGER4PTGDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153327-A | 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |