Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 3/20 | 0.33 |
| ▸ | F3 | P13726 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718363 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL19276329 | 0.80 | TSHR (0.35) | ALDH1A1TSHRACLYCYP2D6CYP2C19 | |
| SCHEMBL18203203 | 0.80 | ALDH1A1 (0.35) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL1786337 | 0.80 | ALDH1A1 (0.31) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL18203204 | 0.80 | ALDH1A1 (0.35) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL1786335 | 0.80 | ALDH1A1 (0.31) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL3898173 | 0.78 | CYP2D6 (0.50) | ALDH1A1TSHRACLYCYP2D6CYP2C19 | |
| SCHEMBL21292006 | 0.78 | FFAR1 (0.30) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL21292007 | 0.78 | FFAR1 (0.30) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL3898176 | 0.78 | CYP2D6 (0.50) | ALDH1A1TSHRACLYCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170239212-A1 | BRYOSTATIN ANALOGS AND USE THEREOF AS ANTIVIRAL AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-24 | — | — | US | disclosed |
| EP-0293053-B1 | PROCESS FOR THE PREPARATION OF CYCLIC CARBOXYLIC ANHYDRIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-04 | — | — | EP | disclosed |
| EP-0293053-A2 | Process for the preparation of cyclic carboxylic anhydrides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170239212-A1 | BRYOSTATIN ANALOGS AND USE THEREOF AS ANTIVIRAL AGENTS | PRKCH, PRKCZ, PRKCB | ALDH1A1 4871/4885CYP19A1 4534/4885MAPT 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.