Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659259 | 0.85 | ALDH1A1 (0.71) | ALDH1A1MAPTTAAR1TBXA2RTBXAS1 | |
| SCHEMBL9718418 | 0.84 | TAAR1 (0.63) | ALDH1A1MAPTTAAR1TBXA2RTBXAS1 | |
| SCHEMBL10463031 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPTTAAR1TBXA2RTBXAS1 | |
| SCHEMBL7505744 | 0.80 | SMN1; SMN2 (0.67) | ALDH1A1MAPTMMEKMT2ANPSR1 | |
| SCHEMBL9660574 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPTTBXA2RTBXAS1MEN1 | |
| SCHEMBL9661175 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTTBXA2RTBXAS1MEN1 | |
| SCHEMBL9659280 | 0.80 | TBXA2R (0.70) | ALDH1A1MAPTTBXA2RTBXAS1PRMT1 | |
| SCHEMBL9659378 | 0.77 | LSS (0.60) | ALDH1A1MAPTTBXA2RTBXAS1CA1 | |
| SCHEMBL10463108 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTTAAR1TBXA2RTBXAS1 | |
| SCHEMBL9718380 | 0.75 | TBXAS1 (0.63) | ALDH1A1MAPTTBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260527-B1 | SYNERGETIC COMBINATION COMPRISING A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A2-ANTAGONIST, AND THEIR USE OR MANUFACTURE | Dr. Karl Thomae GmbH (DE) | 1992-04-01 | — | — | EP | disclosed |