Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463031 | 0.89 | ALDH1A1 (0.64) | TAAR1ALDH1A1MAPTTBXA2RTBXAS1 | |
| SCHEMBL9659259 | 0.88 | ALDH1A1 (0.71) | TAAR1ALDH1A1MAPTTDP1TBXA2R | |
| SCHEMBL9659280 | 0.88 | TBXA2R (0.70) | ALDH1A1MAPTTBXA2RTBXAS1 | |
| SCHEMBL9660574 | 0.88 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNATBXA2RTBXAS1 | |
| SCHEMBL9661175 | 0.88 | ALDH1A1 (0.62) | ALDH1A1MAPTTDP1TBXA2RTBXAS1 | |
| SCHEMBL10699471 | 0.88 | CYP1A2 (0.62) | TAAR1ALDH1A1MAPTLMNACYP1A2 | |
| SCHEMBL9718387 | 0.87 | ALDH1A1 (0.62) | TAAR1ALDH1A1MAPTLMNACYP1A2 | |
| SCHEMBL9718408 | 0.84 | ALDH1A1 (0.59) | TAAR1ALDH1A1MAPTTBXA2RTBXAS1 | |
| SCHEMBL9659378 | 0.84 | LSS (0.60) | ALDH1A1MAPTTBXA2RTBXAS1 | |
| SCHEMBL9777976 | 0.84 | ALDH1A1 (0.59) | TAAR1ALDH1A1MAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260527-B1 | SYNERGETIC COMBINATION COMPRISING A PHOSPHODIESTERASE INHIBITOR AND A THROMBOXAN-A2-ANTAGONIST, AND THEIR USE OR MANUFACTURE | Dr. Karl Thomae GmbH (DE) | 1992-04-01 | — | — | EP | disclosed |
| US-4948809-A | TREATMENT OF AILMENTS DUE TO THROMBOCYTE AGGREGATION OR KIDNEY DYSFUNCTION | BOEHRINGER MANNHEIM GMBH (DE) | 1990-08-14 | — | — | US | disclosed |
| EP-0194548-A2 | Sulfonylaminoethyl compounds, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1986-09-17 | — | — | EP | disclosed |