Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777957 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTNPSR1FFAR1TBXAS1 | |
| SCHEMBL9777991 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNANPSR1FFAR1 | |
| SCHEMBL9778006 | 0.87 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNANPSR1MEP1B | |
| SCHEMBL9777971 | 0.87 | TBXA2R (0.59) | ALDH1A1MAPTNPSR1TBXAS1 | |
| SCHEMBL9777982 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNANPSR1FFAR1 | |
| SCHEMBL9777950 | 0.84 | TSHR (0.59) | ALDH1A1MAPTLMNANPSR1FFAR1 | |
| SCHEMBL9718418 | 0.84 | TAAR1 (0.63) | ALDH1A1MAPTLMNATAAR1TBXAS1 | |
| SCHEMBL23014361 | 0.82 | KAT6A (0.58) | ALDH1A1LMNATAAR1CXCR4MEP1B | |
| SCHEMBL9777983 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNANPSR1POLB | |
| SCHEMBL23014406 | 0.80 | EGFR (0.55) | ALDH1A1MAPTLMNAMEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | claimed |
| US-4999345-A | Anticoagulants | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0345572-A2 | Sulfonamide derivatives, their preparation and pharmaceuticals containing them | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |