Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26673955 | 0.95 | CYP19A1 (0.56) | CA12CA4CA9CYP19A1CA1 | |
| SCHEMBL12517362 | 0.85 | CYP19A1 (0.59) | CA12CA4CA9CYP19A1CA1 | |
| SCHEMBL16561436 | 0.85 | CA12 (0.53) | CA12CA4CA9CYP19A1CA1 | |
| SCHEMBL26673938 | 0.83 | CYP19A1 (0.56) | CA12CA4CA9CYP19A1CA1 | |
| SCHEMBL30640587 | 0.83 | CYP19A1 (0.56) | CA12CA4CA9CYP19A1CA1 | |
| SCHEMBL4398919 | 0.83 | PKM (0.56) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL20273256 | 0.81 | PARP10 (0.59) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL9155792 | 0.81 | L3MBTL1 (0.61) | CA12CA4CA9CA1GSTP1 | |
| SCHEMBL28721563 | 0.81 | CA12 (0.50) | CA12CA4CA9CYP19A1CA1 | |
| SCHEMBL3697699 | 0.81 | GSTP1 (0.42) | CA12CA4CA9CYP19A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989427-B | Polytriazole resin toughened by propargyl polypropylene glycol, preparation method and application thereof | 华东理工大学 | 2023-11-14 | — | — | CN | claimed |
| CN-114989427-A | Polytriazole resin toughened by propargyl polypropylene glycol, and preparation method and application thereof | 华东理工大学 | 2022-09-02 | — | — | CN | claimed |
| CN-114989427-B | Polytriazole resin toughened by propargyl polypropylene glycol, preparation method and application thereof | 华东理工大学 | 2023-11-14 | — | — | CN | disclosed |
| CN-114989427-A | Polytriazole resin toughened by propargyl polypropylene glycol, and preparation method and application thereof | 华东理工大学 | 2022-09-02 | — | — | CN | disclosed |
| US-10450281-B1 | Compounds and methods for treating cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-10-22 | — | — | US | disclosed |
| EP-3424909-A1 | A POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) INHIBITOR AND USES THEREFOR | Washington University (US) | 2019-01-09 | — | — | EP | disclosed |
| US-20180326100-A1 | Radiolabeled Tracers for Poly (ADP-RIBOSE) Polymerase-1 (PARP-1), Methods and Uses Therefor | WASHINGTON UNIVERSITY | 2018-11-15 | — | — | US | disclosed |
| EP-3089965-B1 | RADIOLABELED TRACERS FOR POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1), METHODS AND USES THEREFOR | UNIV WASHINGTON (US) | 2018-08-29 | — | — | EP | disclosed |
| US-9993570-B2 | Radiolabeled tracers for poly (ADP-ribose) polymerase-1 (PARP-1), methods and uses therefor | WASHINGTON UNIVERSITY (US) | 2018-06-12 | — | — | US | disclosed |
| US-9725425-B1 | Compounds and methods for treating cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160339124-A1 | RADIOLABELED TRACERS FOR POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1), METHODS AND USES THEREFOR | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-11-24 | — | — | US | disclosed |
| EP-3089965-A1 | RADIOLABELED TRACERS FOR POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1), METHODS AND USES THEREFOR | Washington University (US) | 2016-11-09 | — | — | EP | disclosed |
| WO-2015103526-A1 | RADIOLABELED TRACERS FOR POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1), METHODS AND USES THEREFOR | WASHINGTON UNIVERSITY (US) | 2015-07-09 | — | — | WO | disclosed |
| US-5155196-A | Derived from propargyl ethers, cyclization to chromenes; waterproof, heat and solvent resistant; structural materials | THE DOW CHEMICAL COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180326100-A1 | Radiolabeled Tracers for Poly (ADP-RIBOSE) Polymerase-1 (PARP-1), Methods and Uses Therefor | PARP4, PARP1, PARP11 | CA12 4012/4885CA4 3329/4885CA9 4295/4885 |
| US-10450281-B1 | Compounds and methods for treating cancer | USP8, USP2, NEDD8 | CA12 327/4885CA4 1454/4885CA9 751/4885 |
| US-20160339124-A1 | RADIOLABELED TRACERS FOR POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1), METHODS AND USES THEREFOR | PARP4, PARP11, PARP1 | CA12 4161/4885CA4 4076/4885CA9 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.