⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849373 | 0.86 | — | — | |
| SCHEMBL8849069 | 0.78 | — | — | |
| SCHEMBL9718533 | 0.77 | LMNA (0.33) | — | |
| SCHEMBL4594892 | 0.73 | — | — | |
| SCHEMBL8849259 | 0.72 | LMNA (0.30) | — | |
| SCHEMBL15915903 | 0.67 | — | — | |
| SCHEMBL8849278 | 0.66 | — | — | |
| SCHEMBL15915164 | 0.65 | TSHR (0.32) | — | |
| SCHEMBL8848879 | 0.65 | — | — | |
| SCHEMBL8849908 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106807-A | Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific | HIMONT INCORPORATED (US) | 1992-04-21 | — | — | US | disclosed |