SCHEMBL8849259

SCHEMBL8849259

CCCC[SiH](CCCC)C(OC)OC

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702627 0.89 DNM1 (0.37) TSHR
SCHEMBL1532318 0.86
SCHEMBL8849373 0.83
SCHEMBL17995580 0.82
SCHEMBL8849027 0.77 THRB (0.35) LMNA
SCHEMBL2927552 0.75
SCHEMBL15915213 0.72 TSHR (0.33) LMNATSHR
SCHEMBL9718540 0.72
SCHEMBL8848879 0.71
SCHEMBL4594892 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671417-B1 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC (US) 1997-05-02 EP disclosed
EP-0437263-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1995-11-08 EP disclosed
EP-0671417-A2 Components and catalysts for the copolymerisation of olefins MONTELL NORTH AMERICA INC. (US) 1995-09-13 EP disclosed
US-5106807-A Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific HIMONT INCORPORATED (US) 1992-04-21 US disclosed
EP-0437263-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1991-07-17 EP disclosed