Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849111 | 0.87 | THRB (0.38) | LMNA | |
| SCHEMBL8849404 | 0.84 | LMNA (0.45) | LMNA | |
| SCHEMBL9718540 | 0.77 | — | — | |
| SCHEMBL8849027 | 0.73 | THRB (0.35) | LMNA | |
| SCHEMBL18787584 | 0.71 | THRB (0.47) | LMNA | |
| SCHEMBL8849099 | 0.67 | LMNA (0.43) | LMNA | |
| SCHEMBL8849042 | 0.66 | LMNA (0.47) | LMNA | |
| SCHEMBL5049804 | 0.66 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL15349124 | 0.66 | THRB (0.36) | LMNA | |
| SCHEMBL8849869 | 0.66 | LMNA (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106807-A | Coordination catalysts comprising a dihydrocarbylethermethyl silane, a titanium halide and a magnesium halide support; stereospecific | HIMONT INCORPORATED (US) | 1992-04-21 | — | — | US | disclosed |