Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718595 | 0.91 | LMNA (0.49) | LMNA | |
| SCHEMBL9718624 | 0.87 | LMNA (0.42) | LMNA | |
| SCHEMBL9718619 | 0.87 | LMNA (0.43) | LMNA | |
| SCHEMBL10518459 | 0.85 | CHRM2 (0.52) | LMNA | |
| SCHEMBL9718607 | 0.82 | CHRM2 (0.48) | LMNA | |
| SCHEMBL9718581 | 0.79 | LMNA (0.44) | LMNA | |
| SCHEMBL9718606 | 0.77 | LMNA (0.44) | LMNA | |
| SCHEMBL9718599 | 0.75 | KCNH2 (0.54) | — | |
| SCHEMBL10518670 | 0.73 | GAA (0.40) | — | |
| SCHEMBL10518016 | 0.73 | LMNA (0.42) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323864-A2 | Lipophilic oxadiazoles | MERCK SHARP & DOHME LTD. (GB) | 1989-07-12 | — | — | EP | claimed |
| US-5135935-A | Anticholesterol agents | MERCK & CO., INC. (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0323864-A2 | Lipophilic oxadiazoles | MERCK SHARP & DOHME LTD. (GB) | 1989-07-12 | — | — | EP | disclosed |