Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718562 | 0.86 | RAB9A (0.59) | KCNH2SMN1; SMN2 | |
| SCHEMBL9718617 | 0.83 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL9718621 | 0.81 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL9718655 | 0.79 | — | — | |
| SCHEMBL9718623 | 0.77 | KCNH2 (0.81) | KCNH2 | |
| SCHEMBL9718605 | 0.75 | LMNA (0.41) | — | |
| SCHEMBL9718610 | 0.74 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL9493360 | 0.72 | CHRNA7 (0.61) | — | |
| SCHEMBL20676389 | 0.72 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4425801 | 0.72 | NR1H4 (0.64) | SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135935-A | Anticholesterol agents | MERCK & CO., INC. (US) | 1992-08-04 | — | — | US | disclosed |