Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718617 | 0.84 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL9718621 | 0.84 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL9718623 | 0.78 | KCNH2 (0.81) | KCNH2 | |
| SCHEMBL6354836 | 0.76 | CHRNA7 (0.55) | — | |
| SCHEMBL9718580 | 0.75 | — | — | |
| SCHEMBL7266942 | 0.75 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL9718599 | 0.74 | KCNH2 (0.54) | KCNH2 | |
| Hydrochloric Acid SCHEMBL1832216 | 0.74 | NR1H4 (0.68) | CNR2CNR1 | |
| SCHEMBL9718562 | 0.73 | RAB9A (0.59) | KCNH2 | |
| SCHEMBL7274207 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135935-A | Anticholesterol agents | MERCK & CO., INC. (US) | 1992-08-04 | — | — | US | disclosed |