Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718599 | 0.86 | KCNH2 (0.54) | SMN1; SMN2KCNH2 | |
| SCHEMBL9718617 | 0.82 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL9718621 | 0.81 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL9718623 | 0.78 | KCNH2 (0.81) | KCNH2 | |
| SCHEMBL9718655 | 0.77 | — | — | |
| SCHEMBL5110768 | 0.75 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL20676557 | 0.75 | RAB9A (0.61) | RAB9ASMN1; SMN2GAAMAPK1GRM5 | |
| SCHEMBL9718610 | 0.73 | KCNH2 (0.55) | KCNH2 | |
| SCHEMBL9718580 | 0.73 | — | — | |
| SCHEMBL9496249 | 0.73 | CHRNA7 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135935-A | Anticholesterol agents | MERCK & CO., INC. (US) | 1992-08-04 | — | — | US | disclosed |