Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315381 | 1.00 | LMNA (0.37) | LMNAMAPK1TSHRCES2CES1 | |
| SCHEMBL9314643 | 0.82 | LMNA (0.38) | LMNAMAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9004975 | 0.82 | LMNA (0.38) | LMNAMAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9718676 | 0.78 | LMNA (0.46) | LMNATSHRCES2CES1KMT2A | |
| SCHEMBL9004751 | 0.77 | LMNA (0.40) | LMNATSHRCES2CES1KMT2A | |
| SCHEMBL9004904 | 0.72 | LMNA (0.36) | LMNAMAPK1TSHRCES2CES1 | |
| SCHEMBL9004647 | 0.71 | ALDH1A1 (0.36) | LMNAMAPK1TSHRCES2CES1 | |
| SCHEMBL9314611 | 0.71 | ALDH1A1 (0.36) | LMNAMAPK1TSHRCES2CES1 | |
| SCHEMBL9718661 | 0.68 | LMNA (0.40) | LMNAMAPK1TSHRCES2CES1 | |
| SCHEMBL9004919 | 0.68 | CES2 (0.46) | CES2CES1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510539-A | LIQUID KETALS; LONG DARK STORAGE STABILITY | CIBA-GEIGY CORPORATION (US) | 1996-04-23 | — | — | US | disclosed |
| EP-0401166-B1 | Nitrogen-containing titanocenes and their use | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | disclosed |
| EP-0401165-B1 | New oxygen-containing titanocenes and their use | CIBA GEIGY AG (CH) | 1994-11-30 | — | — | EP | disclosed |
| US-5306600-A | Oxygen-containing titanocenes, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |
| US-5288917-A | Benzil ketals; end-capped polyoxyyethylene glycol; mixed with titanocene-type initiators | CIBA-GEIGY CORPORATION (US) | 1994-02-22 | — | — | US | disclosed |
| EP-0318894-B1 | Titanocenes, their use and N-substituted pyrroles | CIBA GEIGY AG (CH) | 1994-02-16 | — | — | EP | disclosed |
| EP-0318893-B1 | Titanocenes, their use and N-substituted fluoroanilines | CIBA GEIGY AG (CH) | 1994-01-19 | — | — | EP | disclosed |
| EP-0255486-B1 | TITANOCENES AND THEIR USE | CIBA-GEIGY AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| US-5192642-A | Photoinitiators for addition photopolymerization, coatings | CIBA-GEIGY CORPORATION (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0256981-B1 | TITANOCENES AND THEIR USE | CIBA-GEIGY AG (CH) | 1993-02-17 | — | — | EP | disclosed |
| EP-0401166-A2 | Nitrogen-containing titanocenes and their use | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | disclosed |
| US-4970136-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-11-13 | — | — | US | disclosed |
| US-4963470-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-16 | — | — | US | disclosed |
| EP-0242330-B1 | LIQUID BLEND OF PHOTOINITIATORS | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | disclosed |
| US-4857654-A | Titanocenes and their use | CIBA-GEIGY CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0318893-A2 | Titanocenes, their use and N-substituted fluoroanilines | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| EP-0318894-A2 | Titanocenes, their use and N-substituted pyrroles | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |
| EP-0256981-A2 | Titanocenes and their use | CIBA-GEIGY AG (CH) | 1988-02-24 | — | — | EP | disclosed |
| EP-0255486-A2 | Titanocenes and their use | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |
| EP-0242330-A1 | Liquid blend of photoinitiators | CIBA-GEIGY AG (CH) | 1987-10-21 | — | — | EP | disclosed |