Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22468120 | 0.79 | ALDH1A1 (0.36) | DPP4PARP1PIM1PIM3CLK4 | |
| SCHEMBL22230572 | 0.78 | LMNA (0.42) | DPP4PARP1LMNACOMTMEN1 | |
| SCHEMBL9718690 | 0.78 | MAPK14 (0.38) | PARP1PIM1PIM3CLK4ALDH1A1 | |
| SCHEMBL1480724 | 0.75 | PARP1 (0.41) | DPP4PARP1LMNACOMTMEN1 | |
| SCHEMBL28233407 | 0.74 | PARP1 (0.51) | PARP1LMNACOMTMEN1POLB | |
| SCHEMBL3860252 | 0.74 | DPP4 (0.62) | DPP4PARP1PIM1PIM3CLK4 | |
| SCHEMBL11222589 | 0.73 | PARP1 (0.50) | PARP1LMNACOMTMEN1POLB | |
| Hydrochloric Acid SCHEMBL6318386 | 0.69 | MEN1 (0.54) | PARP1LMNACOMTMEN1POLB | |
| SCHEMBL14762833 | 0.68 | DHODH (0.49) | PARP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22468121 | 0.68 | MAPK14 (0.35) | POLBALDH1A1HSD17B10MAPK14RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144081-A | Sunscreen agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |