Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669212 | 1.00 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL8560242 | 0.89 | RIPK1 (0.46) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7665586 | 0.88 | CHRNB2 (0.44) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7669230 | 0.88 | CHRNA7 (0.49) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7669223 | 0.88 | CHRNA7 (0.49) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7686987 | 0.88 | RIPK1 (0.48) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7669180 | 0.87 | LMNA (0.48) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7660006 | 0.86 | LMNA (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7670029 | 0.85 | KMT2A (0.48) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7669029 | 0.85 | CHRNB2 (0.46) | RIPK1CHRNB2CHRNA4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-5049571-A | Insecticides | CIBA-GEIGY CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| US-4918086-A | PESTICIDES, INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |