Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233316 | 0.84 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL9045175 | 0.82 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL27461815 | 0.81 | KDM4E (0.54) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL29424535 | 0.79 | NPC1 (1.00) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL218892 | 0.79 | NPC1 (1.00) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL7717955 | 0.77 | NPC1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8900536 | 0.76 | F7 (0.60) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL1895948 | 0.74 | NPC1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL30362075 | 0.73 | GUSB (0.68) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2606253 | 0.73 | GUSB (0.68) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151472-A | Dissolving polyetherimides in a solvent, adding a dianhydride and a diamine, reacting to form a polyamic acid and cyclizing to form a polyimide | GENERAL DYNAMICS CORPORATION, CONVAIR DIVISION (US) | 1992-09-29 | — | — | US | disclosed |