Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | CA1 | P00915 | 4/20 | 0.67 |
| ▸ | CA9 | Q16790 | 4/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CA4 | P22748 | 3/20 | 0.67 |
| ▸ | CA7 | P43166 | 3/20 | 0.67 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.67 |
| ▸ | CA6 | P23280 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL10777436 | 0.89 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Phthalic Acid SCHEMBL28139807 | 0.88 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL5693247 | 0.88 | ALDH1A1 (0.78) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL28189123 | 0.86 | ALDH1A1 (0.82) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL4827260 | 0.84 | ALDH1A1 (0.86) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL1810677 | 0.84 | ALDH1A1 (0.86) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL19209758 | 0.84 | ALDH1A1 (0.86) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL5874635 | 0.84 | ALDH1A1 (0.86) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Catechol SCHEMBL29004862 | 0.84 | TDP1 (0.57) | ALDH1A1KDM4EHPGDCA1CA9 | |
| Salicylic Acid SCHEMBL1193531 | 0.84 | ALDH1A1 (0.86) | ALDH1A1KDM4EHPGDCA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4021618-A | — | — | None | — | — | JP | disclosed |
| JP-62240620-A | — | — | None | — | — | JP | disclosed |
| JP-2009807-A | — | — | None | — | — | JP | disclosed |
| JP-H0421618-A | DENTAL ADHESIVE OF PHOTOPOLYMERIZATION TYPE AND ADHESIVE KIT | SOGO SHIKA IRYO KENKYUSHO:KK | 1992-01-24 | — | — | JP | disclosed |
| JP-H029807-A | DENTINE-PROTECTING COMPOSITION | SOGO SHIKA IRYO KENKYUSHO:KK | 1990-01-12 | — | — | JP | disclosed |
| JP-S62240620-A | SEDATIVE FOR TOOTHACHE CONTAINING N-METHACRYLOYL-AMINOSALICYLIC ACID | MASUHARA HIDEKAZU | 1987-10-21 | — | — | JP | disclosed |