Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366859 | 0.86 | TDP1 (0.45) | TSHRPTGS1PTGS2ALOX5TP53 | |
| SCHEMBL4424277 | 0.82 | TSHR (0.65) | TSHRPTGS1PTGS2TP53TDP1 | |
| SCHEMBL28259163 | 0.81 | ALOX5 (0.35) | PTGS1PTGS2ALOX5TDP1ALDH1A1 | |
| SCHEMBL32671491 | 0.81 | MAPT (0.42) | TSHRTDP1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL183161 | 0.81 | MAPT (0.42) | TSHRTDP1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL29392003 | 0.80 | ALOX5 (0.47) | PTGS1PTGS2ALOX5TP53TDP1 | |
| SCHEMBL87447 | 0.80 | ALOX5 (0.47) | PTGS1PTGS2ALOX5TP53TDP1 | |
| SCHEMBL15198 | 0.78 | ALDH1A1 (0.58) | TSHRTDP1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL11034893 | 0.77 | PTGS1 (0.41) | PTGS1PTGS2ALOX5TP53TDP1 | |
| SCHEMBL8527619 | 0.77 | RELA (0.49) | TSHRPTGS1PTGS2ALOX5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091476-A | Fireproofing | THE DOW CHEMICAL COMPANY (US) | 1992-02-25 | — | — | US | claimed |
| EP-0378103-A2 | Cyanate ester resin blends with brominated styrene containingpolymers | THE DOW CHEMICAL COMPANY (US) | 1990-07-18 | — | — | EP | claimed |
| US-5091476-A | Fireproofing | THE DOW CHEMICAL COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0378103-A2 | Cyanate ester resin blends with brominated styrene containingpolymers | THE DOW CHEMICAL COMPANY (US) | 1990-07-18 | — | — | EP | disclosed |