Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719156 | 0.97 | ALDH1A1 (0.40) | CYP11B1CYP11B2CYP19A1ALDH1A1HTR1A | |
| SCHEMBL9719136 | 0.96 | PDE4A (0.41) | CYP11B1CYP11B2CYP19A1ALDH1A1HTR1A | |
| SCHEMBL9719246 | 0.96 | PDE4A (0.41) | CYP11B1CYP11B2CYP19A1ALDH1A1HTR1A | |
| SCHEMBL9719112 | 0.96 | PDE4A (0.41) | CYP11B1CYP11B2CYP19A1ALDH1A1HTR1A | |
| SCHEMBL9719167 | 0.96 | PDE4A (0.41) | CYP11B1CYP11B2CYP19A1ALDH1A1HTR1A | |
| SCHEMBL9719159 | 0.96 | PDE4A (0.41) | CYP11B1CYP11B2CYP19A1ALDH1A1HTR1A | |
| SCHEMBL10943626 | 0.85 | LMNA (0.39) | ALDH1A1TXNRD1MAPTCTSBMEN1 | |
| SCHEMBL10942288 | 0.84 | SMN1; SMN2 (0.39) | TXNRD1MAPTCTSBMEN1KMT2A | |
| SCHEMBL10949964 | 0.84 | SMN1; SMN2 (0.39) | TXNRD1MAPTCTSBMEN1KMT2A | |
| SCHEMBL10949604 | 0.84 | SMN1; SMN2 (0.39) | TXNRD1MAPTCTSBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104885-A | 5-(phenylalkoxy)primaquine and 5[(heterocycle)alkoxy] primaquine compounds and their use for treatment of malaria | CALSPAN CORPORATION (US) | 1992-04-14 | — | — | US | disclosed |
| US-4980360-A | NONTOXIC AT HIGHER DOSAGES | CALSPAN CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |