Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736393 | 0.87 | MAOA (0.50) | MEN1KMT2AMAOAMAOBLMNA | |
| Hydrochloric Acid SCHEMBL9719431 | 0.85 | MEN1 (0.40) | MEN1KMT2AALDH1A1CYP19A1MAOA | |
| SCHEMBL79265 | 0.85 | MAOA (0.48) | MEN1KMT2AMAOAMAOBLMNA | |
| SCHEMBL8111113 | 0.79 | CYP19A1 (0.47) | CYP19A1MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9719344 | 0.78 | CYP19A1 (0.46) | CYP19A1MAPTSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9271782 | 0.75 | CYP19A1 (0.43) | CYP19A1LMNAMAPTCYP2D6GAA | |
| SCHEMBL11879292 | 0.75 | MEN1 (0.46) | MEN1KMT2AALDH1A1MAOAMAOB | |
| SCHEMBL9389645 | 0.74 | ALOX5 (0.41) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL9269160 | 0.72 | CYP19A1 (0.41) | CYP19A1MAOAMAOBCYP1A2CYP3A4 | |
| SCHEMBL9266327 | 0.72 | CYP19A1 (0.41) | CYP19A1MAOAMAOBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000760-A1 | METHOD OF TREATING NEUROLOGICAL DYSFUNCTION USING NEUROTRANSMITTER ENHANCES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-01-23 | — | — | WO | disclosed |