Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79265 | 0.94 | MAOA (0.48) | MAOAMAOBATMLMNAMEN1 | |
| SCHEMBL9719337 | 0.87 | MEN1 (0.45) | MAOAMAOBATMLMNAMEN1 | |
| SCHEMBL13839136 | 0.81 | MAOA (0.39) | MAOAMAOBATMLMNAMEN1 | |
| SCHEMBL9633190 | 0.80 | CYP1A2 (0.51) | ATMLMNAMEN1KMT2AMAPT | |
| SCHEMBL7169479 | 0.79 | LMNA (0.43) | MAOAMAOBATMLMNACYP2C9 | |
| SCHEMBL2885969 | 0.79 | HTT (0.44) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL3088498 | 0.79 | KMT2A (0.40) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL30429168 | 0.77 | MAOB (0.46) | MAOAMAOBNPSR1 | |
| SCHEMBL3092190 | 0.77 | KMT2A (0.37) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL31545658 | 0.76 | LMNA (0.41) | MAOAMAOBATMLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8766242-B2 | Aromatic chalcogen compounds and their use | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120068166-A1 | AROMATIC CHALCOGEN COMPOUNDS AND THEIR USE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-22 | — | — | US | disclosed |
| US-8089064-B2 | Aromatic chalcogen compounds and their use | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090121627-A1 | AROMATIC CHALCOGEN COMPOUNDS AND THEIR USE | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-14 | — | — | US | disclosed |
| US-7504769-B2 | Aromatic chalcogen compounds and their use | E. I. DU PONT DE NEMOURS + COMPANY (US) | 2009-03-17 | — | — | US | disclosed |