Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719500 | 0.95 | HSPA5 (0.35) | HSPA5GABRA1GABRB2 | |
| SCHEMBL9719446 | 0.84 | KEAP1 (0.38) | HTR2A | |
| SCHEMBL9719426 | 0.84 | SLC6A2 (0.35) | HTR2A | |
| SCHEMBL9719519 | 0.80 | BCL2 (0.33) | HTR2A | |
| SCHEMBL9763059 | 0.76 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL9719496 | 0.73 | IDH1 (0.31) | — | |
| SCHEMBL9763293 | 0.73 | TDP1 (0.34) | GAAMAPT | |
| SCHEMBL9719465 | 0.72 | IDH1 (0.30) | — | |
| SCHEMBL9092024 | 0.71 | GABRA1 (0.47) | GAAMAPTGABRA1GABRB2 | |
| SCHEMBL9092458 | 0.69 | GABRA1 (0.32) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227163-B1 | CROSSLINKABLE ELASTOMERIC COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-05-20 | — | — | EP | claimed |
| EP-0227163-A2 | Crosslinkable elastomeric compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-07-01 | — | — | EP | claimed |
| EP-0227163-B1 | CROSSLINKABLE ELASTOMERIC COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-05-20 | — | — | EP | disclosed |
| US-4766180-A | Crosslinked elastomers containing benzocyclobutene derivatives as crosslinking agents | SHELL OIL COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0227163-A2 | Crosslinkable elastomeric compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-07-01 | — | — | EP | disclosed |