SCHEMBL9763293

SCHEMBL9763293

BrCCc1cccc2c1C=C2

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.34
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763059 0.82 GABRA1 (0.31)
SCHEMBL9719500 0.77 HSPA5 (0.35)
SCHEMBL9092458 0.74 GABRA1 (0.32)
SCHEMBL9719425 0.73 HSPA5 (0.37) GAAMAPT
SCHEMBL2965774 0.72 TDP1 (0.34) TDP1
SCHEMBL9719446 0.71 KEAP1 (0.38)
SCHEMBL30600 0.70 TDP1 (0.55) TDP1
SCHEMBL6359390 0.69 TDP1 (0.42) TDP1
SCHEMBL9763721 0.69 HTR1B (0.38)
SCHEMBL5698313 0.68 TDP1 (0.30) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021528-A Crosslinked bisphenol containing arylcyclobutene alkyl ethers and cured compositions therefrom SHELL OIL COMPANY (US) 1991-06-04 US disclosed
US-4943665-A Modified bisphenols containing arylcyclobutenealkyl ethers and cured compositions therefrom SHELL OIL COMPANY (US) 1990-07-24 US disclosed