Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124603 | 0.96 | TSHR (0.37) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL25452830 | 0.92 | TSHR (0.39) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL3910882 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL16914465 | 0.80 | OPRM1 (0.36) | ALDH1A1TSHRHSD17B10CYP3A4TP53 | |
| SCHEMBL7158468 | 0.79 | CTSK (0.37) | ALDH1A1MAPTDPP4OPRM1OPRL1 | |
| SCHEMBL4755383 | 0.78 | TSHR (0.34) | TSHRHSD17B10DPP4TP53MGAM | |
| SCHEMBL17446960 | 0.78 | OPRM1 (0.36) | ALDH1A1MAPTTSHRHSD17B10OPRM1 | |
| SCHEMBL31345064 | 0.77 | TSHR (0.37) | TSHRHSD17B10CYP3A4TP53MGAM | |
| SCHEMBL14559630 | 0.77 | TSHR (0.33) | TSHRHSD17B10DPP4TP53EPHX2 | |
| SCHEMBL2805815 | 0.75 | CYP2C19 (0.45) | KDM4EALDH1A1MAPTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135927-A | 2-chloro-4-trifluoromethylthiazol-5-carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-4992434-A | Prevention of infestation of plants by phytopathogenic microorganisms | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |