Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5713328 | 0.77 | MAPT (0.42) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL5399458 | 0.72 | CES1 (0.38) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL27605410 | 0.71 | HSP90AA1 (0.33) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL11560397 | 0.63 | MAOA (0.41) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL29894137 | 0.63 | CHKA (0.32) | ALDH1A1LMNA | |
| SCHEMBL30945595 | 0.63 | CHKA (0.32) | ALDH1A1LMNA | |
| SCHEMBL29236876 | 0.63 | ALDH1A1 (0.47) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL30547267 | 0.63 | CHKA (0.32) | ALDH1A1LMNA | |
| SCHEMBL30163133 | 0.62 | PNMT (0.52) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| Hydrogen Sulfide SCHEMBL23044042 | 0.61 | CHKA (0.31) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227163-B1 | CROSSLINKABLE ELASTOMERIC COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-05-20 | — | — | EP | claimed |