SCHEMBL971957

SCHEMBL971957

Cc1ccc(CNS(=O)(=O)c2ccc(-c3cc(C(F)(F)F)on3)s2)o1

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.65
MAPT P10636 11/20 0.63
TP53 P04637 2/20 0.63
L3MBTL1 Q9Y468 1/20 0.50
PPARG P37231 1/20 0.43
CCKBR P32239 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL974380 0.84 MAPT (0.48) POLBMAPTTP53RXFP1KMT2A
SCHEMBL972208 0.80 MAPT (0.64) POLBMAPTTP53KMT2A
SCHEMBL15882461 0.77 L3MBTL1 (0.61) POLBMAPTTP53L3MBTL1PPARG
SCHEMBL14569197 0.76 L3MBTL1 (0.67) POLBMAPTTP53L3MBTL1PPARG
SCHEMBL15825036 0.75 MAPT (0.67) POLBMAPTTP53L3MBTL1PPARG
SCHEMBL858210 0.73 MAPT (0.59) POLBMAPTTP53L3MBTL1PPARG
SCHEMBL858579 0.73 MAPT (0.60) POLBMAPTTP53L3MBTL1PPARG
SCHEMBL858487 0.72 MAPT (0.61) POLBMAPTTP53L3MBTL1PPARG
SCHEMBL2764261 0.72 L3MBTL1 (0.65) POLBMAPTTP53L3MBTL1PPARG
SCHEMBL788538 0.72 L3MBTL1 (0.65) POLBMAPTTP53L3MBTL1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds BASF SE (DE) 2011-01-20 US claimed
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds BASF SE (DE) 2011-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds STS, NAPA, NAAA POLB 4080/4885MAPT 3640/4885TP53 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.