Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574205 | 0.92 | HPGD (0.49) | CES2CES1MEN1KMT2AALOX15 | |
| SCHEMBL697540 | 0.78 | MAP4K4 (0.53) | MEN1KMT2AALOX15TSHRHPGD | |
| SCHEMBL28585419 | 0.77 | HPGD (0.53) | MEN1KMT2AALOX15TSHRHPGD | |
| SCHEMBL9628022 | 0.76 | HPGD (0.50) | CES2CES1KMT2ANPC1RAB9A | |
| SCHEMBL27142106 | 0.75 | AKR1C1 (0.41) | MEN1KMT2AALOX15TSHRMAPT | |
| SCHEMBL27147102 | 0.72 | PARP10 (0.41) | MEN1KMT2AALOX15TSHRL3MBTL1 | |
| SCHEMBL2459892 | 0.71 | MAP4K4 (0.57) | MEN1KMT2ARAB9AALOX15TSHR | |
| SCHEMBL14155983 | 0.71 | CES2 (0.50) | CES2CES1ALOX15TSHR | |
| SCHEMBL31117822 | 0.71 | MAP4K4 (0.61) | MEN1KMT2ARAB9AHPGDMAPT | |
| SCHEMBL31117904 | 0.71 | MAP4K4 (0.48) | MEN1KMT2ARAB9AALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198429-B2 | Heterocyclic alkanol-derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-01 | — | — | US | disclosed |
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | BAYER INTELLCTUAL PROPERTY GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-5089640-A | Fungicides, plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4988382-A | HERBICIDES, PLANT GROWTH REGULATORS, IMIDAZOLE DERIVATIVES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| EP-0180136-B1 | SUBSTITUTED AZOLYLMETHYL-CYCLOPROPYL CARBINOL DERIVATIVES | BAYER AG (DE) | 1991-01-02 | — | — | EP | disclosed |
| US-4921528-A | PLANT GROWTH REGULATORS, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |
| EP-0180850-A2 | Antimycotic azolyl-methyl-cyclopropyl-carbinol derivatives | BAYER AG (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180136-A2 | Substituted azolylmethyl-cyclopropyl carbinol derivatives | BAYER AG (DE) | 1986-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140274952-A1 | NOVEL HETEROCYCLIC ALKANOL-DERIVATIVES | ERG28, CBR3, MYB | CES2 2183/4885CES1 2047/4885MEN1 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.