SCHEMBL971959

SCHEMBL971959

NC(=O)c1ccc(C(c2c[nH]cn2)S(=O)(=O)O)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
OPRD1 P41143 1/20 0.32
MKNK1 Q9BUB5 5/20 0.32
MKNK2 Q9HBH9 5/20 0.32
NNMT P40261 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CAMKK2 Q96RR4 1/20 0.32
PARP10 Q53GL7 3/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
PARP15 Q460N3 1/20 0.31
PARP14 Q460N5 1/20 0.31
PARP16 Q8N5Y8 1/20 0.31
PARP11 Q9NR21 1/20 0.31
PARP4 Q9UKK3 1/20 0.31
CDC7 O00311 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11163287 0.84 PARP1 (0.38) PARP10PARP15PARP14CDC7PLK4
SCHEMBL7666295 0.72 OPRD1 (0.38) OPRD1MKNK1MKNK2SMN1; SMN2PARP10
SCHEMBL3963134 0.66 MKNK2 (0.47) CA2CA12CA1CA9CA14
Terephthalamide SCHEMBL693310 0.65 CA2 (0.65) CA2CA12CA1CA9CA14
SCHEMBL11212615 0.63 SMN1; SMN2 (0.33) CA2MKNK1MKNK2NNMTSMN1; SMN2
SCHEMBL7664520 0.63 PLA2G10 (0.50) MKNK1MKNK2NNMTSMN1; SMN2PARP10
SCHEMBL27268295 0.63 HDAC3 (0.41) SMN1; SMN2ALDH1A1KMT2APOLBMAPT
SCHEMBL6328868 0.63 TSHR (0.52) CA2CA12CA1CA9CA14
SCHEMBL7433283 0.62
Hydrochloric Acid SCHEMBL9231395 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds BASF SE (DE) 2011-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015065-A1 Substituted Sulfonic Acid Amide Compounds STS, NAPA, NAAA CA2 1016/4885CA12 1436/4885CA1 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.