Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL1424875 | 0.84 | SLC7A5 (0.68) | TAAR1SLC6A2CYP2C19KDM4EKMT2A | |
| Valine SCHEMBL5324319 | 0.81 | SLC7A5 (0.58) | TAAR1SLC6A2CYP2C19ALDH1A1KMT2A | |
| Tyramine SCHEMBL9616224 | 0.81 | TAAR1 (0.75) | TAAR1SLC6A2CYP2C19KDM4EALDH1A1 | |
| Tyrosine SCHEMBL1684964 | 0.81 | SLC7A5 (0.77) | TAAR1SLC6A2KDM4EALDH1A1ADRA2A | |
| Tyrosine SCHEMBL1585042 | 0.81 | SLC7A5 (0.77) | TAAR1SLC6A2KDM4EALDH1A1ADRA2A | |
| Tyrosine SCHEMBL1684965 | 0.81 | SLC7A5 (0.77) | TAAR1SLC6A2KDM4EALDH1A1ADRA2A | |
| Tyrosine SCHEMBL7101405 | 0.81 | SLC7A5 (0.77) | TAAR1SLC6A2KDM4EALDH1A1ADRA2A | |
| Tyrosine SCHEMBL28992639 | 0.81 | SLC7A5 (0.77) | TAAR1SLC6A2KDM4EALDH1A1ADRA2A | |
| Tyrosine SCHEMBL20238845 | 0.79 | SLC7A5 (0.80) | TAAR1SLC6A2CYP2C19KDM4EALDH1A1 | |
| Tyrosine SCHEMBL16149122 | 0.79 | SLC7A5 (0.80) | TAAR1SLC6A2CYP2C19KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110806-A | Dipalmitoyl phosphatidyl choline, fatty alcohol, tyloxapol | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-05-05 | — | — | US | disclosed |
| US-4826821-A | DIPALITOYLPHOSPHATIDYL CHLOINE, FATTY ALCOHOL, NONIONIC ETHER SURFACTANT, SODIUM CHLORIDE, RESPIROATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-05-02 | — | — | US | disclosed |