Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27536656 | 0.74 | BRD4 (0.52) | BRD4FFAR2SMN1; SMN2GAAHPGD | |
| SCHEMBL9577333 | 0.73 | BRD4 (0.47) | BRD4FFAR2SMN1; SMN2GAAHPGD | |
| SCHEMBL621292 | 0.72 | BRD4 (0.50) | BRD4FFAR2SMN1; SMN2GAAHPGD | |
| SCHEMBL1590331 | 0.72 | PTGS2 (0.61) | BRD4FFAR2ADRB2POLBMEN1 | |
| SCHEMBL598280 | 0.72 | PTGS2 (0.61) | BRD4FFAR2ADRB2POLBMEN1 | |
| SCHEMBL12225982 | 0.72 | BRD4 (0.61) | BRD4FFAR2SMN1; SMN2GAAHPGD | |
| SCHEMBL15695554 | 0.72 | BRD4 (0.61) | BRD4FFAR2SMN1; SMN2GAAHPGD | |
| SCHEMBL121108 | 0.72 | PTGS2 (0.61) | BRD4FFAR2ADRB2POLBMEN1 | |
| SCHEMBL607802 | 0.71 | EPHX1 (0.58) | BRD4FFAR2ADRB2HDAC4HDAC7 | |
| Hydrochloric Acid SCHEMBL5846545 | 0.71 | PTGS2 (0.59) | BRD4FFAR2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079374-A | Cyclopropyl-oxirane compounds as intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-07 | — | — | US | disclosed |
| US-4983208-A | Plant diseases, cereal crops | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |
| EP-0298332-B1 | HYDROXY-ALKYLAZOLYL DERIVATIVES | BAYER AG (DE) | 1990-11-28 | — | — | EP | disclosed |
| US-4925482-A | Fungicidal and plant growth-regulating hydroxyalkyl-azolyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| US-4925865-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0336186-A2 | Derivatives of triazolylmethylcyclopropyl-carbinols as material protecting agents | BAYER AG (DE) | 1989-10-11 | — | — | EP | disclosed |
| EP-0313783-A1 | Antimycotic composition | BAYER AG (DE) | 1989-05-03 | — | — | EP | disclosed |
| EP-0298332-A1 | Hydroxy-alkylazolyl derivatives | BAYER AG (DE) | 1989-01-11 | — | — | EP | disclosed |