Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL851840 | 0.95 | — | — | |
| Potassium Ion SCHEMBL7930144 | 0.95 | KDM4E (0.50) | — | |
| Potassium Ion SCHEMBL8720018 | 0.90 | TSHR (0.46) | — | |
| Silver SCHEMBL9442087 | 0.86 | — | — | |
| SCHEMBL23567016 | 0.84 | KDM4E (0.50) | — | |
| SCHEMBL22749162 | 0.84 | KDM4E (0.50) | — | |
| SCHEMBL4858286 | 0.84 | KDM4E (0.50) | — | |
| SCHEMBL20570963 | 0.84 | KDM4E (0.50) | — | |
| SCHEMBL22581617 | 0.84 | KDM4E (0.50) | — | |
| SCHEMBL243288 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139789-A | Mixture of sodium methanesulfonate, sodium bicarbonate, magnesium chloride, potassium chloride, potassium methanesulfonate and calcium chloride having controlled concentration of potassium and chloride ions | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1992-08-18 | — | — | US | claimed |