Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602451 | 0.88 | PTGS2 (0.56) | PTGS2PTGS1ARSLC6A4SLC6A3 | |
| SCHEMBL1515711 | 0.86 | PDE4A (0.55) | SLC6A4SLC6A3HTTLMNAMAPK1 | |
| SCHEMBL6401188 | 0.83 | MAPK1 (0.49) | PTGS2PTGS1ARHTTLMNA | |
| SCHEMBL1515697 | 0.83 | ALOX5AP (0.59) | ALOX5APFEN1SLC6A4SLC6A3CHEK1 | |
| SCHEMBL27637393 | 0.79 | PTGS2 (0.61) | PTGS2PTGS1ARTUBB1LMNA | |
| SCHEMBL14610404 | 0.78 | ALOX5AP (0.53) | ALOX5APFEN1SLC6A4SLC6A3HTT | |
| SCHEMBL29466480 | 0.77 | HTT (0.62) | HTTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14294261 | 0.77 | RAB9A (0.48) | PTGS2ARHTTTUBB1LMNA | |
| SCHEMBL16539654 | 0.76 | AR (0.48) | PTGS2PTGS1ARHTTLMNA | |
| SCHEMBL17980659 | 0.76 | SMN1; SMN2 (0.56) | HTTLMNARAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098602-A | Aromatic ester derivatives and fluorophenol ketones | NIPPON MINING CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0341686-A2 | Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements | JAPAN ENERGY CORPORATION (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0231853-A2 | Optically active carboxylic acid derivatives and liquid crystalline compositions comprising them | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1987-08-12 | — | — | EP | disclosed |