Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.40 |
| ▸ | KIF11 | P52732 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963521 | 0.77 | CA4 (0.41) | LMNATAAR1HTR2ASLC6A4 | |
| SCHEMBL94 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL29278092 | 0.75 | CA4 (0.39) | TAAR1HTR2ASLC6A4 | |
| Toluene SCHEMBL4171207 | 0.74 | ACHE (0.61) | LMNATSHRALOX12ACHENPC1 | |
| Toluene SCHEMBL4774666 | 0.73 | ACHE (0.69) | LMNATSHRALOX12ACHETAAR1 | |
| Toluene SCHEMBL3861980 | 0.73 | ACHE (0.69) | LMNATSHRALOX12ACHETAAR1 | |
| Toluene SCHEMBL14637534 | 0.73 | LMNA (0.52) | LMNATSHRALOX12ACHETAAR1 | |
| Toluene SCHEMBL9799867 | 0.72 | ACHE (0.79) | LMNATSHRALOX12ACHENPC1 | |
| Bromide SCHEMBL10832798 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL10834720 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153196-A | Administering for reduction of neurotransmission in nervous system disorders | ELI LILLY AND COMPANY (US) | 1992-10-06 | — | — | US | disclosed |