Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | CA9 | Q16790 | 7/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720236 | 0.87 | CES2 (0.38) | TLR2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL9720217 | 0.83 | MEN1 (0.51) | LPAR1LPAR3DNM1TLR2USP2 | |
| SCHEMBL7135483 | 0.79 | TSHR (0.45) | LPAR1LPAR3DNM1TLR2KDM4E | |
| SCHEMBL7135487 | 0.79 | TSHR (0.45) | LPAR1LPAR3DNM1TLR2KDM4E | |
| Hydrochloric Acid SCHEMBL10557205 | 0.77 | PRKD3 (0.45) | LPAR1LPAR3DNM1ALDH1A1LMNA | |
| SCHEMBL25299196 | 0.76 | ALDH1A1 (0.44) | LPAR1LPAR3TLR2ALDH1A1LMNA | |
| SCHEMBL25405618 | 0.76 | ALDH1A1 (0.44) | LPAR1LPAR3TLR2ALDH1A1LMNA | |
| SCHEMBL18720002 | 0.76 | TSHR (0.45) | LPAR1LPAR3DNM1KDM4EUSP2 | |
| SCHEMBL10552379 | 0.76 | PRKD3 (0.42) | LPAR1LPAR3KDM4EUSP2ALDH1A1 | |
| SCHEMBL20895660 | 0.75 | TSHR (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081245-A | Selective antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0356765-A2 | Carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |